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2017-05-10

When modeling subcellular signaling pathways, experimental data are integrated into a precise and structured framework from which it is possible to make predictions that could be tested experimentally. However, the quantitative experimental data...

2014-05-08

Activation of the protein kinase ERK and the subunit GluR1 of the glutamate-gated AMPAR channels in dendritic spines of D1R+ medium spiny neurons is triggered by dopamine acting via D1R couple to Golf through two different signaling cascades....